Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
Tottenham Hotspur brutally exposed Liverpool's defensive frailties as Harry Kane plundered two more goals in his side's 4-1 romp at Wembley on Sunday.
A round-up of Tuesday's action in the UEFA Champions League.
Raheem Sterling struck twice as the Premier League champions Manchester City beat Crystal Palace 3-1 at Selhurst Park on Sunday to stay within two points of leaders Liverpool.
Liverpool's Mohamed Salah is willing to put his Champions League ambitions on the back-burner to help the Merseyside club claim their first English league crown in 29 years, the Egyptian forward has said.
Second-half goals from Willian and Diego Costa helped Chelsea ease past Hull City 2-0 on Saturday and grab their first win in four Premier League games.
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
The three teams with 100 percent records in this season's Champions League can secure their places in the knockout stage this week with two games to spare.
Images from Sunday's English Premier League matches.
Teenager Curtis Jones grabbed a 58th-minute winner as an injury-hit Liverpool qualified for the knockout stage of the Champions League with a 1-0 win over Ajax Amsterdam at Anfield on Tuesday.
An inspired Matteo Darmian scored his first goal for Manchester United and set up another as Louis van Gaal's side kept alive their hopes of a top-four finish with a 2-0 home win over Crystal Palace on Wednesday.
News of all that's transpired on and off the football field.
Tottenham Hotspur reached the semi-finals of the Champions League on away goals after a 4-3 (aggregate 4-4) defeat to Manchester City in a breathtaking quarter-final second leg game on Wednesday.
Tottenham moved up to seventh place with 36 points from 22 games
Ranieri had recognised his future at the West London side was uncertain after Wednesday's stinging 2-0 defeat at Southampton.
Mohamed Salah struck four times in rampant Liverpool's 5-0 thrashing of Watford that lifted them back into third spot in the Premier League on Saturday.
Barcelona and Atletico Madrid led a Spanish Armada into the Champions League last 16 with home wins on Wednesday and in-form Aaron Ramsey steadied Arsenal's boat with a battling win against rocky Borussia Dortmund.
Sergio Aguero scored a hat-trick as free-scoring Manchester City climbed to the top of the Premier League with an irresistible 6-0 victory against Watford on Saturday.
A summary of Sunday's Premier League matches
News of all that's transpired on and off the football field
Images from the Champions League matches played on Tuesday
Images from the English Premier League matches played on Wednesday.
Bernardo Silva has made an encouraging start to the Premier League campaign and the Manchester City midfielder said that feeling more settled at his second season with the champions was a key factor in his performances.
Manchester United flirted with calamity before coasting into the Europa League last 16 as debutant Marcus Rashford helped them overcome an early blow with two goals in a 5-1 home victory over Midtjylland on Thursday.
IMAGES from the English Premier League matches played on Saturday.
News of all that's transpired on and off the football field
New Liverpool boss Juergen Klopp made it three wins from his last three matches with a 1-0 success at Rubin Kazan in Russia that left them second in Group B, two points behind Swiss club Sion on Thursday.
Title-chasing Tottenham Hotspur made hay in the sunshine as Son Heung-min scored twice in a 4-0 thrashing of Watford that closed the gap on Premier League leaders Chelsea to four points in Saturday's early kickoff.
Images from the English Premier League matches played on Saturday
Barca captain Messi opened the scoring with a "Panenka" penalty chipped straight down the middle in the 17th minute after Luis Suarez was fouled in the area, putting the home side ahead in the tie after a goalless first leg in France.
Tottenham Hotspur fluffed their last-day lines with a 5-1 defeat at relegated, 10-man Newcastle United that left them third in the Premier League behind bitter north London rivals Arsenal.
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
Juventus rehire Allegri.
This and more from the happenings in the world of football
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Images from the EPL matches played on Sunday
Luka Modric pulled one back for Zinedine Zidane's shellshocked side with a brilliant strike from distance early in the second half before substitute Vinicius Jr reduced the deficit to one goal.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.